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Fan Cheng Microsoft has developed a plasma robot to help develop new crown specific drugs

Опубликован в:2020-04-26

Novel coronavirus pneumonia has been published on novel coronavirus pneumonia, and Microsoft has recently published an article on its official website to help survivors become heroes. It urged new champions of pneumonia to donate plasma, and through its plasma to study the treatment of new crown pneumonia, it completed cooperation with CoVIg-19 Plasma Alliance research group.


The treatment of injecting convalescent plasma into newly infected people is called plasma infusion therapy, which has a long history of use. As early as the 1890s, people used it to treat diphtheria; This treatment also worked during the 1918 influenza pandemic; Plasma infusion therapy also has therapeutic effects on SARS, leprosy and chicken pox.


In the course of novel coronavirus pneumonia, plasma infusion therapy has also been shown to speed up recovery. Therefore, further in-depth research is necessary.


1、 Microsoft called on the rehabilitation patients to donate as soon as possible and also launched the "plasma robot"


Novel coronavirus pneumonia is the first to novel coronavirus pneumonia, and Microsoft urged the new crown pneumonia rehabilitant to donate plasma. "The earlier the new crown pneumonia rehabilitates, the sooner the plasma can be donated, and the sooner the researcher can start studying the possible treatment and clinical trials," he said.


The blog also pointed out that donating plasma is not cumbersome. In the United States, member companies of covig-19 plasma alliance have 500 operation centers, and more than 50% of eligible donors live within 15 miles of an operation center.


In addition, Microsoft also launched the "plasma robot". Before collecting blood, each donor needs to pass antibody screening to determine whether there is covid-19 virus antibody in his blood. Plasma robot can provide this service and save human resources.


Microsoft said it would promote "plasma robot" through covig-19 official website and other networks, social networking and search channels. Microsoft called on everyone to introduce the project to potential donors, "so that we can all play our part in promoting change."


2、 Polyclonal high immunoglobulin therapy has more clinical advantages
In the process of fighting COVID-19, rehabilitative plasma has two ways of using it. The first is to deliver plasma containing antibodies directly to patients. The second is to use plasma in a wider range for polyclonal high immunoglobulin (h-ig) treatment.


During the production of h-ig, a variety of plasma are mixed together, and the antibody is concentrated to a consistent and reliable level.


H-ig therapy has four benefits:
1. The drug dose injected into the patient is low;
2. Compared with the direct delivery of plasma, the time required for h-ig is shorter;
3. In the process of immunoglobulin production, strict virus inactivation and removal steps should be carried out to avoid transmitting the virus or bacteria in the donor to the patient;
4. H-ig has a longer shelf life and is easy to store and transport.


Therefore, the medical community generally believes that h-ig therapy has more advantages in clinic, and it is necessary to study how to produce h-ig on a large scale. Covig-19 plasma alliance proposed a scheme.


3、 The first-class blood products company formed a research group to promote the new progress of h-ig therapy
It is understood that covig-19 plasma alliance is a research institution composed of world-class blood products companies, including biotest, BPL, LFB, octapharm, CSL Behring and Takeda. The letters "I" and "g" in covig-19 represent "immunoglobulin".




The protocol of covig-19 plasma alliance is divided into three steps: plasma collection, clinical trial development and product manufacturing.


After evaluation, Microsoft believes that the scheme is effective. "We are convinced that the covig-19 plasma alliance has a real opportunity to save lives on a large scale, and may be faster than the methods currently studied." The blog wrote.


Therefore, Microsoft and the Gates Foundation supported the research group. It is reported that the bill and Melinda Gates Foundation is responsible for the financial support of the research group, and Microsoft will help the research group collect the plasma of rehabilitated patients.


Microsoft supports CoVIg-19 Plasma Alliance for the study of polyclonal high immunoglobulin in COVID-19, and is expected to introduce a reliable treatment plan to provide hope for the infected and reduce the burden on the medical system. It is reported that Microsofts donor recruitment is currently carried out in the United States and will be extended to Europe later.

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